Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28216507 | 0.79 | KCNH2 (0.42) | ALDH1A1KMT2ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL31415660 | 0.74 | KMT2A (0.46) | EPHX2BRD4ALDH1A1MAPTKMT2A | |
| SCHEMBL28258545 | 0.70 | EPHX2 (0.41) | EPHX2SIRT1BRD4ALDH1A1MAPT | |
| SCHEMBL30129300 | 0.69 | HPGD (0.40) | EPHX2SIRT1BRD4ALDH1A1MAPT | |
| SCHEMBL28215922 | 0.68 | KCNMA1 (0.42) | ALDH1A1MAPTKMT2APOLBSMN1; SMN2 | |
| SCHEMBL28175330 | 0.68 | ALDH1A1 (0.49) | EPHX2ALDH1A1MAPTKMT2APOLB | |
| SCHEMBL30020367 | 0.67 | IDO1 (0.41) | EPHX2BRD4ALDH1A1MAPTKMT2A | |
| SCHEMBL8806228 | 0.66 | BRD4 (0.44) | BRD4ALDH1A1MAPTKMT2APOLB | |
| SCHEMBL10176168 | 0.65 | ALDH1A1 (0.45) | ALDH1A1MAPTKMT2ACYP2C9L3MBTL1 | |
| SCHEMBL8807200 | 0.65 | ALDH1A1 (0.56) | BRD4ALDH1A1MAPTKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108033922-A | A kind of preparation method of 3- acyl groups quinokysalines derivative | 河南工业大学 | 2018-05-15 | — | — | CN | disclosed |