Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 1/20 | 0.54 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24173124 | 0.93 | GNAI3 (0.49) | GPR183TEAD3GNAI3GNAO1GNAI1 | |
| SCHEMBL1286435 | 0.89 | TEAD3 (0.46) | GPR183TEAD3FGFR1FGFR4FGFR2 | |
| SCHEMBL11293146 | 0.84 | GPR183 (0.40) | GPR183TEAD3S1PR1S1PR3S1PR5 | |
| SCHEMBL22849040 | 0.82 | GPR183 (0.40) | GPR183TEAD3USP2S1PR1S1PR3 | |
| SCHEMBL4910222 | 0.81 | GPR183 (0.46) | GPR183USP2GNAI3GNAO1GNAI1 | |
| SCHEMBL16281588 | 0.81 | TEAD3 (0.53) | GPR183TEAD3HRH2HRH1FGFR1 | |
| SCHEMBL23328270 | 0.81 | TEAD3 (0.47) | GPR183TEAD3FGFR1FGFR4FGFR2 | |
| SCHEMBL1435236 | 0.80 | GPR183 (0.49) | GPR183 | |
| SCHEMBL28215940 | 0.80 | GPR183 (0.49) | GPR183GNAI3GNAO1GNAI1S1PR1 | |
| Hydrochloric Acid SCHEMBL8006371 | 0.79 | TEAD3 (0.43) | GPR183TEAD3HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107586896-A | A kind of thermal stimulus response type acrylic hydrogel leather composite tanning agent and preparation method | 浙江盛汇化工有限公司 | 2018-01-16 | — | — | CN | claimed |
| CN-107586896-A | A kind of thermal stimulus response type acrylic hydrogel leather composite tanning agent and preparation method | 浙江盛汇化工有限公司 | 2018-01-16 | — | — | CN | disclosed |