Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4936620 | 0.76 | KMT2A (0.55) | KMT2AALDH1A1MEN1HPGDFAAH | |
| SCHEMBL6916227 | 0.74 | KMT2A (0.50) | KMT2AALDH1A1MEN1HPGDFAAH | |
| SCHEMBL28373028 | 0.74 | HTT (0.59) | KMT2AMAPTALDH1A1RAB9AMEN1 | |
| SCHEMBL28357823 | 0.74 | KMT2A (0.53) | KMT2AALDH1A1MEN1HPGDFAAH | |
| SCHEMBL9507552 | 0.73 | KMT2A (0.45) | KMT2AALDH1A1MEN1HPGDFAAH | |
| SCHEMBL28041171 | 0.73 | KMT2A (0.52) | KMT2AALDH1A1MEN1HPGDFAAH | |
| SCHEMBL9040129 | 0.73 | KMT2A (0.52) | KMT2AALDH1A1MEN1HPGDFAAH | |
| SCHEMBL27727049 | 0.73 | S100A9 (0.36) | ALDH1A1IDO1 | |
| SCHEMBL18243673 | 0.72 | ALDH1A1 (0.39) | KMT2AMAPTALDH1A1MEN1IDO1 | |
| SCHEMBL16726995 | 0.72 | ALDH1A1 (0.39) | KMT2AMAPTALDH1A1MEN1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105263490-B | Substituted triazolopyridines and methods of use | 基因泰克公司 | 2018-05-22 | — | — | CN | disclosed |