Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506543 | 0.81 | HTT (0.45) | KMT2ACA1CA2CA5ACA9 | |
| SCHEMBL9040129 | 0.78 | KMT2A (0.52) | KMT2APRSS1PRSS2PRSS3FAAH | |
| SCHEMBL4936620 | 0.78 | KMT2A (0.55) | KMT2APRSS1PRSS2PRSS3FAAH | |
| SCHEMBL28357823 | 0.76 | KMT2A (0.53) | KMT2APRSS1PRSS2PRSS3FAAH | |
| SCHEMBL9506595 | 0.76 | — | — | |
| SCHEMBL9505412 | 0.76 | TDP1 (0.35) | KMT2AHPGDCA1CA2ALDH1A1 | |
| SCHEMBL28041171 | 0.75 | KMT2A (0.52) | KMT2APRSS1PRSS2PRSS3FAAH | |
| SCHEMBL10950994 | 0.73 | KMT2A (0.50) | KMT2APRSS1PRSS2PRSS3FAAH | |
| SCHEMBL6916227 | 0.73 | KMT2A (0.50) | KMT2APRSS1PRSS2PRSS3FAAH | |
| SCHEMBL28216045 | 0.73 | KMT2A (0.42) | KMT2APRSS1PRSS2PRSS3FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337820-B1 | PENTAFLUOROPHENYL DERIVATIVES, METHODS OF PRODUCTION OF SUCH DERIVATIVES INCLUDING OPTICALLY ACTIVE DERIVATIVES, AND METHOD OF OPTICAL RESOLUTION OF CHIRAL CARBOXYLIC ACIDS | NIKKO KYODO CO., LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |
| US-5041641-A | Pentafluorophenyl derivatives, methods of production thereof, and method of optical resolution of chiral carboxylic acids | NIPPON MINING COMPANY LIMITED (JP) | 1991-08-20 | — | — | US | disclosed |
| EP-0337820-A1 | Pentafluorophenyl derivatives, methods of production of such derivatives including optically active derivatives, and method of optical resolution of chiral carboxylic acids | NIKKO KYODO CO., LTD. (JP) | 1989-10-18 | — | — | EP | disclosed |