Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.50 |
| ▸ | HTR3B | O95264 | 3/20 | 0.50 |
| ▸ | HTR3A | P46098 | 3/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.50 |
| ▸ | PLAU | P00749 | 2/20 | 0.50 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6344641 | 0.83 | PLAU (0.50) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL11769629 | 0.81 | CYP2D6 (0.56) | CYP2D6HIF1AHTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL11769626 | 0.81 | CYP2D6 (0.56) | CYP2D6HIF1AHTR3EHTR3BHTR3A | |
| SCHEMBL11771956 | 0.80 | CYP2D6 (0.56) | CYP2D6HIF1AHTR3EHTR3BHTR3A | |
| SCHEMBL9047575 | 0.79 | GRIN2B (0.51) | CYP2D6HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL28216249 | 0.76 | HTR3E (0.47) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL4853050 | 0.74 | CYP2D6 (0.85) | CYP2D6HIF1AHTR3EHTR3BHTR3A | |
| SCHEMBL11789365 | 0.74 | CYP2D6 (0.85) | CYP2D6HIF1AHTR3EHTR3BHTR3A | |
| SCHEMBL4617280 | 0.73 | NOS3 (0.55) | HIF1ARAB9AL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL30873946 | 0.73 | F2 (0.57) | RAB9AL3MBTL1SMN1; SMN2HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108084110-A | 3- amino benzo [d] isothiazole, derivative and its synthetic method | 湘潭大学 | 2018-05-29 | — | — | CN | claimed |