Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.47 |
| ▸ | HTR3B | O95264 | 2/20 | 0.47 |
| ▸ | HTR3A | P46098 | 2/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EBP | Q15125 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11773003 | 0.85 | SIGMAR1 (0.51) | SIGMAR1GRIN2BGRIN2DGRIN3BGRIN1 | |
| SCHEMBL11772996 | 0.85 | SIGMAR1 (0.51) | SIGMAR1GRIN2BGRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL11775039 | 0.84 | SIGMAR1 (0.50) | SIGMAR1GRIN2BGRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL11775044 | 0.84 | SIGMAR1 (0.50) | SIGMAR1GRIN2BGRIN2DGRIN3BGRIN1 | |
| SCHEMBL10767060 | 0.79 | ALDH1A1 (0.55) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL18938851 | 0.79 | RAB9A (0.44) | GRIN2BKMT2AALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL28216082 | 0.76 | CYP2D6 (0.54) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL11769546 | 0.76 | NOS3 (0.46) | SIGMAR1GRIN2BGRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL11769550 | 0.76 | NOS3 (0.46) | SIGMAR1GRIN2BGRIN2DGRIN3BGRIN1 | |
| SCHEMBL674743 | 0.75 | SIGMAR1 (0.41) | SIGMAR1GRIN2BGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108084110-A | 3- amino benzo [d] isothiazole, derivative and its synthetic method | 湘潭大学 | 2018-05-29 | — | — | CN | claimed |