SCHEMBL28216092

SCHEMBL28216092

N#Cc1ccc(S(=O)(=O)F)cc1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.55
CA1 P00915 6/20 0.55
CA9 Q16790 4/20 0.55
CA12 O43570 3/20 0.55
CYP19A1 P11511 2/20 0.48
MAOA P21397 2/20 0.44
MAOB P27338 2/20 0.44
IDO1 P14902 1/20 0.44
PTGS2 P35354 1/20 0.44
MAPT P10636 1/20 0.44
RAD51 Q06609 1/20 0.43
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP2A6 P11509 1/20 0.42
CA3 P07451 1/20 0.42
CA6 P23280 1/20 0.42
CA14 Q9ULX7 1/20 0.42
BCHE P06276 1/20 0.42
ACHE P22303 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8514633 0.80 CA2 (0.59) CA2CA1CA9CA12CYP19A1
SCHEMBL11574176 0.79 TSHR (0.56) CA2CA1CA9CA12ALDH1A1
SCHEMBL1894003 0.78 CA2 (0.57) CA2CA1CA9CA12CYP19A1
SCHEMBL1332778 0.78 CA2 (0.57) CA2CA1CA9CA12CYP19A1
SCHEMBL17161292 0.78 F2 (0.43) CA2CA1CA9CA12CA14
SCHEMBL61854 0.76 CA1 (0.55) CA2CA1CA9CA12CYP19A1
SCHEMBL8779787 0.76 CA2 (0.55) CA2CA1CA9CA12CYP19A1
SCHEMBL803901 0.76 PTGS2 (0.68) CA2CA1CA9CA12CYP19A1
Silver SCHEMBL4326545 0.76 CA2 (0.55) CA2CA1CA9CA12CYP19A1
SCHEMBL28445682 0.76 CA2 (0.55) CA2CA1CA9CA12CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113603619-A Method for preparing aryl sulfonyl fluoride by taking aryl hydrazine hydrochloride as raw material 上海应用技术大学 2021-11-05 CN claimed
CN-107935802-A A kind of method that biaryl compound is prepared using arylsulfonyl fluorine as raw material 遵义医学院 2018-04-20 CN claimed
CN-117024237-A Aryl sulfonyl fluoride and preparation method using aryl iodonium salt as raw material 上海应用技术大学 2023-11-10 CN disclosed