Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17A | Q9UEE5 | 3/20 | 0.53 |
| ▸ | STK17B | O94768 | 2/20 | 0.53 |
| ▸ | SIRT5 | Q9NXA8 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CDC25A | P30304 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10229480 | 0.86 | STK17A (0.55) | STK17ASTK17BSIRT5L3MBTL1ALDH1A1 | |
| SCHEMBL27635199 | 0.84 | SIRT5 (0.46) | STK17ASTK17BSIRT5KMT2AKDM4E | |
| SCHEMBL5246243 | 0.83 | STK17B (0.49) | STK17ASTK17BSIRT5KDM4ECA12 | |
| SCHEMBL2060563 | 0.83 | STK17A (0.53) | STK17ASTK17BSIRT5L3MBTL1ALDH1A1 | |
| SCHEMBL25231087 | 0.82 | JAK3 (0.43) | STK17ASTK17BSIRT5KMT2AKDM4E | |
| SCHEMBL30800589 | 0.81 | KMT2A (0.46) | STK17ASTK17BSIRT5KMT2AKDM4E | |
| SCHEMBL27087775 | 0.81 | KMT2A (0.46) | STK17ASTK17BSIRT5KMT2AKDM4E | |
| SCHEMBL21352288 | 0.80 | STK17A (0.63) | STK17ASTK17BSIRT5 | |
| SCHEMBL21352293 | 0.80 | STK17A (0.67) | STK17ASTK17BSIRT5 | |
| SCHEMBL1938460 | 0.80 | STK17A (0.51) | STK17ASTK17BKDM4EL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105399686-B | Pyrimidine derivatives, its preparation method and its application | 深圳微芯生物科技有限责任公司 | 2018-05-22 | — | — | CN | disclosed |