Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | PTGFR | P43088 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2820980 | 0.86 | HRH4 (0.37) | MAPTKMT2AKDM4EMEN1USP2 | |
| SCHEMBL2819742 | 0.86 | KDM1A (0.33) | MAPTKDM4EALDH1A1 | |
| SCHEMBL2826586 | 0.81 | MAPT (0.33) | PTGS2MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL2712340 | 0.80 | MAPT (0.33) | PTGS2MAPTPTGFR | |
| SCHEMBL2820687 | 0.78 | AR (0.33) | — | |
| SCHEMBL2822064 | 0.75 | PTGS2 (0.36) | PTGS2MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL2126008 | 0.72 | KDM4E (0.51) | MAPTKMT2AKDM4EMEN1USP2 | |
| Ethane SCHEMBL6695707 | 0.72 | MAPT (0.37) | PTGS2MAPTALDH1A1 | |
| SCHEMBL1148175 | 0.71 | KMT2A (0.46) | MAPTKMT2AKDM4EMEN1USP2 | |
| SCHEMBL1149078 | 0.71 | CCNC (0.37) | PTGS2MAPTKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1386914-B1 | HALOGENATED QUINOLINE DERIVATIVES AND ECTOPARASITE CONTROLLERS | MEIJI SEIKA KAISHA (JP) | 2010-10-27 | — | — | EP | disclosed |
| CN-1310889-C | Halogen-substituted quinoline derivatives and ectoparasite control agent | MEIJI SEIKA KAISHA (JP) | 2007-04-18 | — | — | CN | disclosed |
| US-7022855-B2 | Halogen-substituted quinoline derivatives and ectoparasite control agent | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-04-04 | — | — | US | disclosed |
| CN-1688193-A | Mixed compositions for controlling parasitic insects | MEIJI SEIKA KAISHA (JP) | 2005-10-26 | — | — | CN | disclosed |
| EP-1559321-A1 | MIXED COMPOSITIONS FOR CONTROLLING PARASITIC INSECTS | MEIJI SEIKA KAISHA LTD. (JP) | 2005-08-03 | — | — | EP | disclosed |
| CN-1501918-A | Halogen-substituted quinoline derivatives and ectoparasite control agent | �����Ƹ���ʽ���� | 2004-06-02 | — | — | CN | disclosed |
| US-20040087618-A1 | Halogen-substituted quinoline derivatives and ectoparasite control agent | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-05-06 | — | — | US | disclosed |
| US-20040077602-A1 | Mixture composition for controlling ectoparasites | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-04-22 | — | — | US | disclosed |
| EP-1386914-A1 | HALOGENATED QUINOLINE DERIVATIVES AND ECTOPARASITE CONTROLLERS | MEIJI SEIKA KAISHA LTD. (JP) | 2004-02-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087618-A1 | Halogen-substituted quinoline derivatives and ectoparasite control agent | ATL3, RABL3, RAB5C | PTGS2 4672/4885MAPT 4564/4885KMT2A 1368/4885 |
| US-20040077602-A1 | Mixture composition for controlling ectoparasites | SF3A3, PEX3, HCN3 | PTGS2 4763/4885MAPT 4378/4885KMT2A 1494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.