Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | ALPL | P05186 | 2/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | MPL | P40238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348302 | 0.77 | MAOB (0.49) | MAOBMAOA | |
| SCHEMBL18530968 | 0.74 | ELANE (0.34) | MAOBMAOA | |
| SCHEMBL29678611 | 0.74 | CA12 (0.33) | MAOBMAOATRPA1 | |
| SCHEMBL28216620 | 0.74 | S1PR1 (0.34) | HRH4S1PR1 | |
| SCHEMBL2296131 | 0.71 | TRPA1 (0.34) | MAOBMAOATRPA1 | |
| SCHEMBL16426152 | 0.70 | GPR35 (0.37) | MAOBMAOA | |
| SCHEMBL3372189 | 0.69 | MAOB (0.46) | MAOBMAOA | |
| SCHEMBL14741951 | 0.67 | NMT1 (0.32) | MAOBMAOA | |
| SCHEMBL7487069 | 0.67 | MAOB (0.38) | MAOBMAOA | |
| SCHEMBL1064292 | 0.67 | MAOA (0.37) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440515-A | Substituted benzofuranyl and benzoxazole based compound and application thereof | 卡尔约药物治疗公司 | 2018-08-24 | — | — | CN | disclosed |
| CN-105492437-B | Substituted benzofuranyl and benzoxazolyl compounds and uses thereof | 卡尔约药物治疗公司 | 2018-05-11 | — | — | CN | disclosed |