Acrylic Acid Methyl Ester

Acrylic Acid Methyl Ester

SCHEMBL28217162

C=CC(=O)OC.C=Cc1ccccc1Cl

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.60
GSR P00390 1/20 0.50
MAOB P27338 3/20 0.47
TSHR P16473 1/20 0.47
MAPT P10636 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
HDAC1 Q13547 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
HPGD P15428 1/20 0.42
ACHE P22303 1/20 0.40
KDM4E B2RXH2 1/20 0.40
GAA P10253 1/20 0.40
ABCG2 Q9UNQ0 1/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
NOS3 P29474 1/20 0.39
NOS1 P29475 1/20 0.39
NOS2 P35228 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid Methyl Ester SCHEMBL28166951 0.88 NFE2L2 (0.40) ALDH1A1GSRTSHRMAPTKDM4E
Acrylic Acid Methyl Ester SCHEMBL2089667 0.88 NFE2L2 (0.40) ALDH1A1GSRTSHRMAPTKDM4E
1,2-Dichlorobenzene SCHEMBL27863989 0.88 TSHR (0.49) ALDH1A1GSRMAOBTSHRMAPT
Acrylic Acid Methyl Ester SCHEMBL27652895 0.87 SMN1; SMN2 (0.46) ALDH1A1GSRMAOBTSHRMAPT
Acrylic Acid Methyl Ester SCHEMBL27552597 0.83 THRB (0.40) TSHRKDM4EGAA
Acrylic Acid Methyl Ester SCHEMBL27522901 0.81 ALDH1A1 (0.42) ALDH1A1TSHRMEN1KMT2AHPGD
Acrylic Acid Methyl Ester SCHEMBL28100202 0.81 THRB (0.39) ALDH1A1TSHRKDM4E
Acrylic Acid Methyl Ester SCHEMBL27821855 0.81 TSHR (0.43) ALDH1A1GSRTSHRMAPTMEN1
SCHEMBL11864735 0.81 ALDH1A1 (0.56) ALDH1A1GSRMAOBTSHRMAPT
Acrylic Acid SCHEMBL28253418 0.80 ALDH1A1 (0.72) ALDH1A1GSRMAOBMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104181786-B Developing toner for electrostatic latent images, the manufacture method of developing toner for electrostatic latent images and electronic photographic image forming method 柯尼卡美能达株式会社 2018-05-08 CN disclosed