SCHEMBL28217196

SCHEMBL28217196

CC1CCCO1.Nc1cc(Cl)cc(Cl)c1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACLY P53396 1/20 0.40
ALDH1A1 P00352 5/20 0.39
HPGD P15428 3/20 0.39
KDM4E B2RXH2 2/20 0.39
HSD17B10 Q99714 3/20 0.37
CYP3A4 P08684 2/20 0.37
TSHR P16473 2/20 0.37
RECQL P46063 2/20 0.37
MAOA P21397 2/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
VCP P55072 1/20 0.33
HTT P42858 3/20 0.33
MEN1 O00255 2/20 0.33
ALOX15 P16050 2/20 0.33
KMT2A Q03164 2/20 0.33
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 3/20 0.32
MAPT P10636 3/20 0.32
LMNA P02545 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexane SCHEMBL28986919 0.77 TSHR (0.56) ACLYALDH1A1HPGDKDM4EHSD17B10
SCHEMBL2253709 0.75 TSHR (0.65) ACLYALDH1A1HPGDKDM4EHSD17B10
Hydrochloric Acid SCHEMBL4969887 0.73 TSHR (0.62) ACLYALDH1A1HPGDKDM4EHSD17B10
Parachlorophenol SCHEMBL28067634 0.71 ALDH1A1 (0.41) ALDH1A1HPGDKDM4EHSD17B10KMT2A
Chlorobenzene SCHEMBL27956885 0.67 TSHR (0.42) ALDH1A1HPGDTSHRHTTMEN1
Methyl Alcohol SCHEMBL2002219 0.67
Hydrogen Peroxide SCHEMBL11406484 0.67
SCHEMBL2473867 0.66 NOS2 (0.35) CA1
SCHEMBL31673148 0.66
SCHEMBL10067 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108059602-B Preparation method of pentachlorosalilamine intermediate 2-amino-4, 6-dichlorophenol organic solution 常州齐晖药业有限公司 2023-04-21 CN disclosed
CN-108059602-A A kind of preparation method of oxyclozanide intermediate 2-amino -4,6- chlorophenesic acid organic solution 常州齐晖药业有限公司 2018-05-22 CN disclosed