Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2253709 | 0.93 | TSHR (0.65) | TSHRALDH1A1HSD17B10CYP3A4RECQL | |
| Hydrochloric Acid SCHEMBL4969887 | 0.91 | TSHR (0.62) | TSHRALDH1A1HSD17B10CYP3A4RECQL | |
| SCHEMBL10884338 | 0.80 | ALDH1A1 (0.52) | TSHRALDH1A1HSD17B10CYP3A4RECQL | |
| SCHEMBL28217196 | 0.77 | ACLY (0.40) | TSHRALDH1A1HSD17B10CYP3A4RECQL | |
| Toluene SCHEMBL28217187 | 0.77 | ALDH1A1 (0.45) | TSHRALDH1A1HSD17B10CYP3A4RECQL | |
| SCHEMBL8872103 | 0.74 | HSD17B10 (1.00) | TSHRALDH1A1HSD17B10CYP3A4RECQL | |
| SCHEMBL184648 | 0.74 | HSD17B10 (1.00) | TSHRALDH1A1HSD17B10CYP3A4RECQL | |
| SCHEMBL2806380 | 0.73 | TTR (0.65) | TSHRALDH1A1HSD17B10CYP3A4RECQL | |
| SCHEMBL13681641 | 0.73 | ALDH1A1 (0.46) | TSHRALDH1A1HSD17B10CYP3A4RECQL | |
| SCHEMBL6687463 | 0.73 | THRB (0.75) | TSHRALDH1A1HSD17B10CYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108059602-B | Preparation method of pentachlorosalilamine intermediate 2-amino-4, 6-dichlorophenol organic solution | 常州齐晖药业有限公司 | 2023-04-21 | — | — | CN | disclosed |