Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28217235 | 1.00 | MEN1 (0.36) | MEN1KMT2ATDP1GABRA1GABRG2 | |
| SCHEMBL28217215 | 0.97 | KCNQ2 (0.32) | MEN1KMT2ATDP1HTR2CHTR2B | |
| SCHEMBL28217217 | 0.97 | KCNQ2 (0.32) | MEN1KMT2ATDP1HTR2CHTR2B | |
| SCHEMBL8990154 | 0.88 | GABRA1 (0.43) | MEN1KMT2ATDP1GABRA1GABRG2 | |
| SCHEMBL28152053 | 0.86 | ALDH1A1 (0.43) | MEN1KMT2ATDP1TSHRSLC6A2 | |
| SCHEMBL28217231 | 0.86 | CNR2 (0.36) | MEN1KMT2ATDP1LMNACYP1A2 | |
| SCHEMBL28217234 | 0.86 | CNR2 (0.36) | MEN1KMT2ATDP1LMNACYP1A2 | |
| SCHEMBL28217676 | 0.82 | LMNA (0.38) | MEN1KMT2ATDP1LMNACYP1A2 | |
| SCHEMBL28217678 | 0.82 | LMNA (0.38) | MEN1KMT2ATDP1LMNACYP1A2 | |
| SCHEMBL28217243 | 0.80 | CNR2 (0.33) | GABRA1GABRG2GABRB3FAAHCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108017559-B | Benzene ring derivative and application thereof in medicine | 四川海思科制药有限公司 | 2020-08-04 | — | — | CN | disclosed |
| CN-108017559-A | Phenyl ring derivative and its application in medicine | 四川海思科制药有限公司 | 2018-05-11 | — | — | CN | disclosed |