Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PPID | Q08752 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446250 | 0.95 | NPSR1 (0.60) | NPSR1ADORA3SMN1; SMN2TDP1PPID | |
| SCHEMBL3835577 | 0.90 | MEN1 (0.55) | NPSR1ADORA3SMN1; SMN2TDP1PPID | |
| SCHEMBL28858391 | 0.86 | ADORA3 (0.56) | NPSR1ADORA3SMN1; SMN2TDP1PPID | |
| SCHEMBL28514782 | 0.85 | NPSR1 (0.54) | NPSR1ADORA3SMN1; SMN2TDP1PPID | |
| SCHEMBL25297216 | 0.81 | APAF1 (0.53) | NPSR1ADORA3SMN1; SMN2PPIDLMNA | |
| SCHEMBL25831273 | 0.81 | APAF1 (0.53) | NPSR1ADORA3SMN1; SMN2PPIDLMNA | |
| SCHEMBL4679533 | 0.80 | KMT2A (0.55) | SMN1; SMN2TDP1LMNAMEN1KMT2A | |
| SCHEMBL7111411 | 0.80 | TOP2A (0.55) | NPSR1SMN1; SMN2LMNAMDM4MAPT | |
| SCHEMBL10424997 | 0.80 | NPSR1 (0.55) | NPSR1ADORA3SMN1; SMN2TDP1PPID | |
| SCHEMBL25267822 | 0.79 | NPSR1 (0.48) | NPSR1ADORA3SMN1; SMN2PPIDMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107986978-A | A kind of preparation method of cardiotonic agents Sha Kubi song intermediates | 临沂齐泽医药技术有限公司 | 2018-05-04 | — | — | CN | claimed |