Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446250 | 0.84 | NPSR1 (0.60) | KMT2AMEN1TDP1LMNASMN1; SMN2 | |
| SCHEMBL2408159 | 0.84 | APAF1 (0.57) | KMT2AMEN1LMNASMN1; SMN2HTT | |
| SCHEMBL6809830 | 0.84 | APAF1 (0.57) | KMT2AMEN1LMNASMN1; SMN2HTT | |
| SCHEMBL2408156 | 0.84 | APAF1 (0.57) | KMT2AMEN1LMNASMN1; SMN2HTT | |
| SCHEMBL10620736 | 0.83 | KCNA5 (0.51) | KMT2AMEN1GAATSHRLMNA | |
| SCHEMBL3547381 | 0.83 | TDP1 (0.48) | KMT2AMEN1TSHRTDP1LMNA | |
| SCHEMBL1768929 | 0.82 | KMT2A (0.46) | KMT2AMEN1GAATSHRLMNA | |
| Methylene Chloride SCHEMBL28217271 | 0.80 | NPSR1 (0.57) | KMT2AMEN1TDP1LMNASMN1; SMN2 | |
| SCHEMBL2793715 | 0.80 | GRM7 (0.58) | KMT2AMEN1TSHRTDP1LMNA | |
| SCHEMBL29045009 | 0.80 | ALDH1A1 (0.54) | KMT2AMEN1GAATDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112939841-B | Synthesis method of (2S) -2-N-fluorenylmethoxycarbonyl amino-4- (3-chlorophenyl) butyric acid | 康化（上海）新药研发有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-117903045-A | Synthesis method of (2S) -2-N-fluorenylmethoxycarbonyl amino-3- [4- (2-pyridine) phenyl ] propionic acid | 康化（上海）新药研发有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-116606223-A | Synthesis method of (2S) -2-N-fluorenylmethoxycarbonyl amino-6, 6-dimethyl N-heptanoic acid | 康化（上海）新药研发有限公司 | 2023-08-18 | — | — | CN | claimed |
| CN-112939841-B | Synthesis method of (2S) -2-N-fluorenylmethoxycarbonyl amino-4- (3-chlorophenyl) butyric acid | 康化（上海）新药研发有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-112939841-B | Synthesis method of (2S) -2-N-fluorenylmethoxycarbonyl amino-4- (3-chlorophenyl) butyric acid | 康化（上海）新药研发有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-117903045-A | Synthesis method of (2S) -2-N-fluorenylmethoxycarbonyl amino-3- [4- (2-pyridine) phenyl ] propionic acid | 康化（上海）新药研发有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-117903045-A | Synthesis method of (2S) -2-N-fluorenylmethoxycarbonyl amino-3- [4- (2-pyridine) phenyl ] propionic acid | 康化（上海）新药研发有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-116606223-A | Synthesis method of (2S) -2-N-fluorenylmethoxycarbonyl amino-6, 6-dimethyl N-heptanoic acid | 康化（上海）新药研发有限公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-116606223-A | Synthesis method of (2S) -2-N-fluorenylmethoxycarbonyl amino-6, 6-dimethyl N-heptanoic acid | 康化（上海）新药研发有限公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-115260060-A | Synthesis method of (2S) -2-N-fluorenylmethoxycarbonylamino-5, 5-dimethyl norleucine | 康化（上海）新药研发有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-111448199-A | Novel highly active amino-thiazole-substituted indole-2-carboxamides having activity against Hepatitis B Virus (HBV) | 艾库里斯有限及两合公司 | 2020-07-24 | — | — | CN | disclosed |
| EP-0945448-B1 | 5-ALKOXY-2(3H)-OXAZOLONE COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | UBE INDUSTRIES (JP) | 2008-11-26 | — | — | EP | disclosed |
| US-6020496-A | 5-alkoxy-2(3H)-oxazolone compounds and process for preparing the same | UBE INDUSTRIES, LTD. (JP) | 2000-02-01 | — | — | US | disclosed |
| EP-0945448-A1 | 5-ALKOXY-2(3H)-OXAZOLONE COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | UBE INDUSTRIES, LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |
| EP-0037271-B1 | INDOLE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | TORAY INDUSTRIES, INC. (JP) | 1984-01-18 | — | — | EP | disclosed |