SCHEMBL6064666

SCHEMBL6064666

CC(C)c1cc(C(C)C)c(CP)c(C(C)C)c1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.45
GABRB2 P47870 1/20 0.45
FABP4 P15090 3/20 0.43
FABP3 P05413 2/20 0.43
FABP5 Q01469 1/20 0.42
SOAT2 O75908 1/20 0.35
MYC P01106 1/20 0.35
SOAT1 P35610 1/20 0.35
MAP2K3 P46734 1/20 0.35
GABRB1 P18505 1/20 0.33
GABRG2 P18507 2/20 0.32
GABRB3 P28472 2/20 0.32
ROCK2 O75116 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28217295 0.78 GABRA1 (0.46) GABRA1GABRB2FABP4FABP3FABP5
SCHEMBL8127965 0.76 GABRA1 (0.58) GABRA1GABRB2FABP4FABP3FABP5
SCHEMBL4877230 0.76 GABRA1 (0.45) GABRA1GABRB2FABP4FABP3FABP5
SCHEMBL8134393 0.76 GABRA1 (0.45) GABRA1GABRB2FABP4FABP3FABP5
SCHEMBL8136838 0.76 GABRA1 (0.45) GABRA1GABRB2FABP4FABP3FABP5
SCHEMBL25219460 0.76 GABRA1 (0.45) GABRA1GABRB2FABP4FABP3FABP5
SCHEMBL8498609 0.74 GABRA1 (0.43) GABRA1GABRB2FABP4FABP3FABP5
SCHEMBL31415928 0.73 GABRA1 (0.42) GABRA1GABRB2FABP4FABP3FABP5
SCHEMBL6064031 0.72 GABRA1 (0.50) GABRA1GABRB2FABP4FABP3FABP5
SCHEMBL2464191 0.71 FABP4 (0.44) GABRA1GABRB2FABP4FABP3FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7030200-B2 Catalysts for olefin polymerization E.I. DU PONT DE NEMOURS AND COMPANY (US) 2006-04-18 US disclosed
US-20050245702-A1 Catalysts for olefin polymerization UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2005-11-03 US disclosed
WO-2003076450-A1 CATALYSTS FOR OLEFIN POLYMERIZATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-09-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050245702-A1 Catalysts for olefin polymerization PNMT, PPOX, ETFA GABRA1 4105/4885GABRB2 3632/4885FABP4 2840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.