Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31317623 | 0.98 | SLC6A3 (0.46) | SLC6A3KCNH2ALDH1A1ECE1KDM4E | |
| SCHEMBL3849941 | 0.90 | SLC6A3 (0.48) | SLC6A3KCNH2ALDH1A1ECE1KDM4E | |
| Acetic Acid SCHEMBL7508639 | 0.89 | SLC6A3 (0.46) | SLC6A3KCNH2ECE1KDM4EADRB3 | |
| SCHEMBL25653945 | 0.89 | SLC6A3 (0.50) | SLC6A3KCNH2ALDH1A1ECE1KDM4E | |
| SCHEMBL6235049 | 0.89 | KCNH2 (0.50) | SLC6A3KCNH2ALDH1A1ECE1KDM4E | |
| SCHEMBL28578070 | 0.87 | SLC6A3 (0.46) | SLC6A3KCNH2ALDH1A1ECE1KDM4E | |
| SCHEMBL11926805 | 0.86 | SLC6A3 (0.49) | SLC6A3DRD2HTR2AHRH1HDAC1 | |
| SCHEMBL9381449 | 0.85 | SLC6A3 (0.45) | SLC6A3KCNH2ALDH1A1ECE1KDM4E | |
| SCHEMBL19197711 | 0.85 | KCNH2 (0.46) | SLC6A3KCNH2ALDH1A1KDM4EDRD2 | |
| SCHEMBL21699960 | 0.84 | SLC6A3 (0.52) | SLC6A3KCNH2ALDH1A1DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240890-A1 | Novel benzamidine derivatives, process for the preparation thereof and pharmaceutical composition comprising the same | DONG WHA PHARMACEUTICAL IND. CO., LTD. | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240890-A1 | Novel benzamidine derivatives, process for the preparation thereof and pharmaceutical composition comprising the same | CMA1, IL5, HRH4 | SLC6A3 4768/4885KCNH2 1537/4885ALDH1A1 1751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.