Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3849941 | 0.98 | SLC6A3 (0.48) | KCNH2SLC6A3ALDH1A1ADRB3ADRB2 | |
| SCHEMBL25653945 | 0.96 | SLC6A3 (0.50) | KCNH2SLC6A3ALDH1A1ADRB3ADRB2 | |
| SCHEMBL28578070 | 0.94 | SLC6A3 (0.46) | KCNH2SLC6A3ALDH1A1ADRB3ADRB2 | |
| SCHEMBL21699960 | 0.92 | SLC6A3 (0.52) | KCNH2SLC6A3ALDH1A1HDAC1HDAC6 | |
| SCHEMBL14226438 | 0.91 | KCNH2 (0.48) | KCNH2SLC6A3ALDH1A1ADRB3ADRB2 | |
| SCHEMBL31317623 | 0.91 | SLC6A3 (0.46) | KCNH2SLC6A3ALDH1A1ADRB3ADRB2 | |
| SCHEMBL19197711 | 0.89 | KCNH2 (0.46) | KCNH2SLC6A3ALDH1A1ADRB3ADRB2 | |
| SCHEMBL2821735 | 0.89 | SLC6A3 (0.47) | KCNH2SLC6A3ALDH1A1ADRB3ADRB2 | |
| SCHEMBL10971781 | 0.88 | SLC6A3 (0.45) | KCNH2SLC6A3ALDH1A1ADRB3ADRB2 | |
| SCHEMBL30665041 | 0.86 | SLC6A3 (0.51) | KCNH2SLC6A3ALDH1A1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1281388-B1 | Cosmetic and dermatological light protection formulations containing 2,2'-(1,4-phenylene)bis-1H-benzimidazole-4,6-disulphonic acid and or its salts and latex particles | BEIERSDORF AG (DE) | 2005-05-04 | — | — | EP | disclosed |