Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.67 |
| ▸ | CA1 | P00915 | 7/20 | 0.67 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.52 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | IL2 | P60568 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7516005 | 1.00 | CA2 (0.67) | CA2CA1LNPEPCA12CA9 | |
| SCHEMBL7517089 | 0.95 | CA2 (0.61) | CA2CA1LNPEPCA12CA9 | |
| SCHEMBL7712141 | 0.92 | CA2 (0.74) | CA2CA1CA12CA9PTPN1 | |
| SCHEMBL7557432 | 0.89 | CA1 (0.54) | CA2CA1LNPEPCA12CA9 | |
| SCHEMBL4054766 | 0.88 | CA2 (0.77) | CA2CA1LNPEPCA12CA9 | |
| SCHEMBL8671997 | 0.88 | CA2 (0.77) | CA2CA1LNPEPCA12CA9 | |
| SCHEMBL4054764 | 0.88 | CA2 (0.77) | CA2CA1LNPEPCA12CA9 | |
| SCHEMBL13091302 | 0.88 | CA2 (0.71) | CA2CA1LNPEPCA12CA9 | |
| SCHEMBL16144960 | 0.87 | CA2 (0.64) | CA2CA1LNPEPCA12CA9 | |
| SCHEMBL16144963 | 0.87 | CA2 (0.64) | CA2CA1LNPEPCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106045932-B | A kind of compound and its application with radiosensitizing effect | 浙江省肿瘤医院 | 2018-05-15 | — | — | CN | disclosed |