Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.61 |
| ▸ | CA1 | P00915 | 6/20 | 0.61 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.53 |
| ▸ | MME | P08473 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 2/20 | 0.50 |
| ▸ | CPA1 | P15085 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | IL2 | P60568 | 1/20 | 0.48 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28217500 | 0.95 | CA2 (0.67) | CA2CA1LNPEPCA12CA9 | |
| SCHEMBL7516005 | 0.95 | CA2 (0.67) | CA2CA1LNPEPCA12CA9 | |
| SCHEMBL7712141 | 0.87 | CA2 (0.74) | CA2CA1MMECA12CA9 | |
| SCHEMBL7554729 | 0.85 | CTSL (0.55) | CA2CA1LNPEPCTSL | |
| SCHEMBL7516942 | 0.84 | CTSL (0.53) | CA2CA1LNPEPCTSL | |
| SCHEMBL7557432 | 0.84 | CA1 (0.54) | CA2CA1LNPEPMMECA12 | |
| SCHEMBL4054764 | 0.84 | CA2 (0.77) | CA2CA1LNPEPMMECTSL | |
| SCHEMBL8671997 | 0.84 | CA2 (0.77) | CA2CA1LNPEPMMECTSL | |
| SCHEMBL4054766 | 0.84 | CA2 (0.77) | CA2CA1LNPEPMMECTSL | |
| SCHEMBL13091302 | 0.84 | CA2 (0.71) | CA2CA1LNPEPCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362165-B1 | Hydroxyphenyl derivatives with HIV integrase inhibitory properties | PHARMACOR INC. (CA) | 2002-03-26 | — | — | US | disclosed |
| EP-1165492-A1 | HYDROXYPHENYL DERIVATIVES WITH HIV INTEGRASE INHIBITORY PROPERTIES | Pharmacor Inc. (CA) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059867-A1 | HYDROXYPHENYL DERIVATIVES WITH HIV INTEGRASE INHIBITORY PROPERTIES | PHARMACOR INC. (CA) | 2000-10-12 | — | — | WO | disclosed |