Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 5/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2820981 | 0.92 | ERN1 (0.47) | ERN1GRM5FFAR1 | |
| SCHEMBL2821756 | 0.87 | GRM5 (0.41) | ERN1PTGESAKR1C3GRM5FFAR1 | |
| SCHEMBL2068612 | 0.82 | PTGDR2 (0.56) | PTGESAKR1C3FFAR1PTGDR2 | |
| SCHEMBL2822197 | 0.82 | GRM5 (0.43) | GRM5FFAR1 | |
| SCHEMBL2820978 | 0.78 | GRM5 (0.44) | ERN1GRM5 | |
| SCHEMBL2068429 | 0.73 | PTGDR2 (0.53) | FFAR1PTGDR2 | |
| SCHEMBL11758794 | 0.71 | TP53 (0.45) | — | |
| SCHEMBL2068734 | 0.69 | PPARA (0.40) | GRM5FFAR1PTGDR2 | |
| SCHEMBL2827415 | 0.69 | GRM5 (0.44) | GRM5FFAR1 | |
| SCHEMBL2822191 | 0.69 | GRM5 (0.43) | GRM5FFAR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745003-B1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-10-27 | — | — | EP | claimed |