Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28217672 | 1.00 | DPP4 (0.32) | DPP4NR1H2NR1H3ANPEP | |
| SCHEMBL28217261 | 0.96 | DPP4 (0.36) | DPP4NR1H2NR1H3ANPEP | |
| SCHEMBL28217262 | 0.96 | DPP4 (0.36) | DPP4NR1H2NR1H3ANPEP | |
| SCHEMBL28045533 | 0.80 | GABRA1 (0.46) | DPP4NR1H2NR1H3ANPEP | |
| SCHEMBL28217238 | 0.78 | TSHR (0.43) | — | |
| SCHEMBL28217237 | 0.78 | TSHR (0.43) | — | |
| SCHEMBL28217217 | 0.76 | KCNQ2 (0.32) | — | |
| SCHEMBL28217215 | 0.76 | KCNQ2 (0.32) | — | |
| SCHEMBL19112120 | 0.74 | SLC6A2 (0.34) | — | |
| SCHEMBL28217235 | 0.74 | MEN1 (0.36) | DPP4NR1H2NR1H3ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108017559-B | Benzene ring derivative and application thereof in medicine | 四川海思科制药有限公司 | 2020-08-04 | — | — | CN | disclosed |
| CN-108017559-A | Phenyl ring derivative and its application in medicine | 四川海思科制药有限公司 | 2018-05-11 | — | — | CN | disclosed |