Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.69 |
| ▸ | MEN1 | O00255 | 7/20 | 0.69 |
| ▸ | KCNK3 | O14649 | 6/20 | 0.65 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28860008 | 0.92 | MEN1 (0.76) | KMT2AMEN1KCNK3KCNK9RAB9A | |
| SCHEMBL2385408 | 0.91 | KMT2A (0.83) | KMT2AMEN1KCNK3KCNK9RAB9A | |
| SCHEMBL22589002 | 0.83 | SIRT1 (0.79) | KMT2AMEN1KCNK3KCNK9RAB9A | |
| SCHEMBL29800565 | 0.82 | MEN1 (0.93) | KMT2AMEN1KCNK3KCNK9RAB9A | |
| SCHEMBL11675529 | 0.82 | MEN1 (1.00) | KMT2AMEN1KCNK3KCNK9RAB9A | |
| SCHEMBL6793906 | 0.82 | MEN1 (0.93) | KMT2AMEN1KCNK3KCNK9RAB9A | |
| SCHEMBL3656361 | 0.80 | NPC1 (0.78) | KMT2AMEN1KCNK3KCNK9RAB9A | |
| SCHEMBL21707396 | 0.80 | MEN1 (0.89) | KMT2AMEN1KCNK3KCNK9RAB9A | |
| SCHEMBL2063559 | 0.80 | KMT2A (0.77) | KMT2AMEN1KCNK3KCNK9RAB9A | |
| SCHEMBL28218536 | 0.80 | KCNK3 (0.60) | KMT2AMEN1KCNK3KCNK9RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107973727-A | Between disubstituted benzenes phenolic compounds and preparation method thereof and anti-tubercle bacillus application | 中山大学 | 2018-05-01 | — | — | CN | claimed |
| CN-107973727-A | Between disubstituted benzenes phenolic compounds and preparation method thereof and anti-tubercle bacillus application | 中山大学 | 2018-05-01 | — | — | CN | disclosed |