Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.43 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL14918555 | 0.89 | NAPRT (0.56) | NAPRTKMT2AMEN1ALDH1A1KDM4E | |
| Pyrazole SCHEMBL3228113 | 0.84 | CYP17A1 (0.44) | NAPRTKMT2AMEN1ALDH1A1PLOD2 | |
| Niacin SCHEMBL9679976 | 0.81 | ALDH1A1 (0.70) | KMT2AALDH1A1PLOD2CYP1A2CYP3A4 | |
| Isoniazid SCHEMBL28826289 | 0.80 | KDM4E (0.68) | ALDH1A1PLOD2PLOD3CYP1A2CYP3A4 | |
| Isonicotinic Acid SCHEMBL1414914 | 0.79 | NAPRT (1.00) | NAPRTKMT2AMEN1ALDH1A1PLOD2 | |
| Isonicotinic Acid SCHEMBL1108 | 0.79 | — | — | |
| Isophthalic Acid SCHEMBL15572677 | 0.79 | CD74 (0.47) | NAPRTALDH1A1CYP1A2CYP2C9HPGD | |
| Isophthalic Acid SCHEMBL15572076 | 0.79 | CD74 (0.47) | NAPRTALDH1A1CYP1A2CYP2C9HPGD | |
| Isonicotinic Acid SCHEMBL28136907 | 0.79 | NAPRT (0.71) | NAPRTKMT2AMEN1ALDH1A1PLOD2 | |
| Isonicotinic Acid SCHEMBL8358038 | 0.78 | NAPRT (0.85) | NAPRTKMT2AMEN1ALDH1A1PLOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907318-B | Isonicotinic acid-pyrazole derivative and preparation method and application thereof | 郑州大学 | 2023-08-11 | — | — | CN | claimed |
| CN-114907318-A | Isonicotinic acid-pyrazole derivative and preparation method and application thereof | 郑州大学 | 2022-08-16 | — | — | CN | claimed |
| CN-114907318-B | Isonicotinic acid-pyrazole derivative and preparation method and application thereof | 郑州大学 | 2023-08-11 | — | — | CN | disclosed |
| CN-114907318-B | Isonicotinic acid-pyrazole derivative and preparation method and application thereof | 郑州大学 | 2023-08-11 | — | — | CN | disclosed |
| CN-114907318-B | Isonicotinic acid-pyrazole derivative and preparation method and application thereof | 郑州大学 | 2023-08-11 | — | — | CN | disclosed |
| CN-114907318-A | Isonicotinic acid-pyrazole derivative and preparation method and application thereof | 郑州大学 | 2022-08-16 | — | — | CN | disclosed |
| CN-114907318-A | Isonicotinic acid-pyrazole derivative and preparation method and application thereof | 郑州大学 | 2022-08-16 | — | — | CN | disclosed |
| CN-114907318-A | Isonicotinic acid-pyrazole derivative and preparation method and application thereof | 郑州大学 | 2022-08-16 | — | — | CN | disclosed |
| CN-108077305-B | Hydrogen peroxide compound disinfectant, use method and application | 中国人民解放军陆军防化学院 | 2020-09-11 | — | — | CN | disclosed |
| CN-110261376-A | The solution and method that ammonium ion interferes chromogenic reaction in removal water sample cyanide content continuous mode | 桂林理工大学 | 2019-09-20 | — | — | CN | disclosed |
| CN-108333127-A | The assay method of cyanide is easily discharged in the solid waste containing cyanogen of thiocyanate | 长春黄金研究院有限公司 | 2018-07-27 | — | — | CN | disclosed |
| CN-108303492-A | The assay method of cyanide is easily discharged in a kind of solid waste containing cyanogen of sulfur compound | 长春黄金研究院有限公司 | 2018-07-20 | — | — | CN | disclosed |
| CN-108254488-A | Thiocyanate, sulfide solid waste in total cyanide assay method | 长春黄金研究院有限公司 | 2018-07-06 | — | — | CN | disclosed |
| CN-108195997-A | The assay method of total cyanide in solid waste containing cyanogen | 长春黄金研究院有限公司 | 2018-06-22 | — | — | CN | disclosed |
| CN-108077305-A | Hydrogen peroxide Compositional type disinfectant, application method and application | 中国人民解放军陆军防化学院 | 2018-05-29 | — | — | CN | disclosed |
| CN-105699574-B | The detection method of cyanide content in a kind of milk and milk powder | 秦皇岛出入境检验检疫局检验检疫技术中心 | 2018-05-18 | — | — | CN | disclosed |