SCHEMBL28218640

SCHEMBL28218640

C=Cc1c(C(C)C)cc(C(=O)O)cc1C(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP3 P05413 1/20 0.41
FABP4 P15090 1/20 0.41
ACE2 Q9BYF1 2/20 0.40
THRA P10827 3/20 0.40
THRB P10828 3/20 0.40
GABRA1 P14867 1/20 0.40
GABRB1 P18505 1/20 0.40
TPMT P51580 2/20 0.39
RXRA P19793 4/20 0.38
RXRB P28702 2/20 0.38
RXRG P48443 2/20 0.38
HSP90AB1 P08238 2/20 0.37
HSP90AA1 P07900 1/20 0.36
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA7 P43166 2/20 0.35
CA9 Q16790 2/20 0.35
CA14 Q9ULX7 2/20 0.35
LCK P06239 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isopropyl Alcohol SCHEMBL28142316 0.76 GABRA1 (0.59) FABP3FABP4THRATHRBGABRA1
SCHEMBL4319072 0.75 GABRA1 (0.63) FABP3FABP4THRATHRBGABRA1
SCHEMBL16104797 0.74 TPMT (0.48) TPMTCA12CA1CA2CA7
SCHEMBL29054130 0.74 FABP3 (0.45) FABP3FABP4ACE2THRATHRB
SCHEMBL1711083 0.73 FABP4 (0.47) FABP3FABP4GABRA1HSP90AB1CA1
SCHEMBL13989031 0.72 SLC22A8 (0.34) FABP3FABP4ACE2THRATHRB
SCHEMBL22882559 0.71 CA12 (0.41) TPMTCA12CA1CA2CA7
SCHEMBL9988559 0.71 KMT2A (0.50) FABP3FABP4ACE2THRATHRB
SCHEMBL15524731 0.71 CA1 (0.61) FABP3FABP4THRATHRBGABRA1
SCHEMBL3636717 0.71 TPMT (0.50) FABP3FABP4ACE2THRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108117522-A A kind of synthetic method of dicarboxylic acids imidazole salts 遵义医学院 2018-06-05 CN disclosed