Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL87813 | 0.98 | PABPC1 (0.56) | PABPC1KDM4EGAAKEAP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28740125 | 0.96 | PABPC1 (0.55) | PABPC1KDM4EGAAKEAP1ALDH1A1 | |
| SCHEMBL17054695 | 0.86 | HPRT1 (0.52) | PABPC1KDM4EGAAKEAP1ALDH1A1 | |
| SCHEMBL29506423 | 0.84 | PABPC1 (0.59) | PABPC1KDM4EGAAKEAP1ALDH1A1 | |
| SCHEMBL15453221 | 0.84 | PABPC1 (0.59) | PABPC1KDM4EGAAKEAP1ALDH1A1 | |
| SCHEMBL16319787 | 0.82 | PABPC1 (0.54) | PABPC1KDM4EGAAKEAP1ALDH1A1 | |
| SCHEMBL5568841 | 0.80 | ALDH1A1 (0.50) | PABPC1KDM4EGAAKEAP1ALDH1A1 | |
| SCHEMBL11537315 | 0.80 | PABPC1 (0.64) | PABPC1KDM4EGAAKEAP1ALDH1A1 | |
| SCHEMBL28163867 | 0.78 | ROCK1 (0.54) | KDM4EALDH1A1HPGDCYP3A4CYP1A2 | |
| SCHEMBL15949880 | 0.78 | KDM4E (0.48) | PABPC1KDM4EGAAKEAP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108752236-A | SHIP1 conditioning agents and relative method | 阿奎诺克斯药物（加拿大）公司 | 2018-11-06 | — | — | CN | disclosed |
| CN-105026375-B | SHIP1 modulators and methods related thereto | 阿奎诺克斯药物（加拿大）公司 | 2018-06-05 | — | — | CN | disclosed |