SCHEMBL28218698

SCHEMBL28218698

CC1(CCC(=O)O)c2cc3ccccc3n2CC1(F)F

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
OXER1 Q8TDS5 9/20 0.38
ALDH1A1 P00352 1/20 0.38
NR1H2 P55055 1/20 0.34
NR1H3 Q13133 1/20 0.34
MCL1 Q07820 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
KMO O15229 1/20 0.34
SIGMAR1 Q99720 2/20 0.33
CNR2 P34972 1/20 0.33
TERT O14746 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8329532 0.63 SIGMAR1 (0.41) ALDH1A1KMOSIGMAR1
SCHEMBL9658520 0.60 HTR2A (0.41) MCL1SIGMAR1
SCHEMBL10674441 0.59 ALDH1A1 (0.66) ALDH1A1
SCHEMBL14762932 0.59 MCL1 (0.54) OXER1ALDH1A1MCL1HDAC6
SCHEMBL9657619 0.58 OPRM1 (0.36) MCL1SIGMAR1
SCHEMBL9685878 0.58 MAPT (0.43) ALDH1A1
SCHEMBL23996175 0.57 ALDH1A1 (0.32) ALDH1A1
SCHEMBL21469196 0.57 ALDH1A1 (0.62) OXER1ALDH1A1L3MBTL1KMO
SCHEMBL9656483 0.57 HTR2A (0.38) MCL1SIGMAR1
Naphthalene SCHEMBL30124954 0.57 NR4A2 (0.61) ALDH1A1L3MBTL1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108069977-A A kind of synthetic method of fluoroalkyl substituted azole [1,2-a] indoles 福州大学 2018-05-25 CN disclosed