Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.35 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.35 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | RARB | P10826 | 3/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19043821 | 0.80 | EPHX2 (0.48) | ALDH1A1KDM4EHPGDHSD17B10KLKB1 | |
| SCHEMBL27843215 | 0.78 | PPARA (0.55) | ALDH1A1KDM4EHPGDHSD17B10KLKB1 | |
| SCHEMBL14428361 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10KLKB1 | |
| SCHEMBL25280765 | 0.77 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDHSD17B10KLKB1 | |
| SCHEMBL27860827 | 0.77 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDHSD17B10KLKB1 | |
| SCHEMBL27860828 | 0.77 | PTPN1 (0.42) | ALDH1A1KDM4EHPGDHSD17B10KLKB1 | |
| SCHEMBL10284551 | 0.76 | — | — | |
| SCHEMBL1348009 | 0.75 | KLKB1 (0.42) | ALDH1A1KDM4EHPGDHSD17B10KLKB1 | |
| SCHEMBL10284553 | 0.75 | ALDH1A1 (0.30) | ALDH1A1CDC25BCASP6RCE1 | |
| SCHEMBL23374384 | 0.75 | FDPS (0.37) | EPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107973791-A | Condensed ring or tricyclic Arylpyrimidines compound are used as kinase inhibitor | 南京圣和药业股份有限公司 | 2018-05-01 | — | — | CN | disclosed |