Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10284551 | 0.80 | — | — | |
| SCHEMBL23374384 | 0.79 | FDPS (0.37) | — | |
| SCHEMBL9287963 | 0.77 | ALDH1A1 (0.39) | ALDH1A1CDC25BCASP6RCE1 | |
| SCHEMBL6468217 | 0.76 | NOS3 (0.38) | ALDH1A1 | |
| SCHEMBL28218974 | 0.75 | ALDH1A1 (0.36) | ALDH1A1CDC25BCASP6RCE1 | |
| SCHEMBL16404803 | 0.74 | TAAR1 (0.42) | ALDH1A1 | |
| SCHEMBL18850328 | 0.72 | SKP2 (0.53) | ALDH1A1 | |
| SCHEMBL14216254 | 0.72 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL7107363 | 0.72 | CA12 (0.38) | ALDH1A1 | |
| SCHEMBL22262276 | 0.72 | HTR1A (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142625-A1 | Substituted Purine And 7-Deazapurine Compounds | Epizyme, Inc. (US) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142625-A1 | Substituted Purine And 7-Deazapurine Compounds | TPMT, DIMT1, DAZAP1 | ALDH1A1 592/4885CDC25B 3536/4885CASP6 3086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.