Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
| ▸ | GNRHR | P30968 | 1/20 | 0.43 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28219655 | 0.81 | ALDH1A1 (0.48) | KDM4EALDH1A1SMN1; SMN2HPGDHTT | |
| SCHEMBL20183800 | 0.81 | KDM4E (0.52) | KDM4EP2RX7PLAUALDH1A1SMN1; SMN2 | |
| SCHEMBL28219647 | 0.79 | KMT2A (0.52) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL12010980 | 0.75 | KMT2A (0.62) | KDM4EALDH1A1SMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL28325706 | 0.74 | LMNA (0.48) | KDM4EALDH1A1SMN1; SMN2HPGDHTT | |
| SCHEMBL4252227 | 0.72 | POLB (0.58) | KDM4EP2RX7PLAUALDH1A1SMN1; SMN2 | |
| SCHEMBL20183743 | 0.72 | KDM4E (0.50) | KDM4EPLAUALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14118359 | 0.72 | LDHA (0.55) | KDM4EPLAUHTTL3MBTL1EGFR | |
| SCHEMBL3467180 | 0.71 | MEN1 (0.53) | KDM4EP2RX7ALDH1A1HTTPOLB | |
| SCHEMBL2470632 | 0.71 | PLAU (0.75) | KDM4EPLAUALDH1A1HTTEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110430878-A | Antitumor agent and bromine structural domain inhibitor | FUJIFILM CORP | 2019-11-08 | — | — | CN | disclosed |
| CN-108137505-A | Nitrogen-containing heterocycle compound | 富士胶片株式会社 | 2018-06-08 | — | — | CN | disclosed |