Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2820325 | 0.86 | TSHR (0.40) | MMP13TSHRTNKSPARP1TNKS2 | |
| SCHEMBL2820531 | 0.85 | OPRL1 (0.37) | MMP13TSHR | |
| SCHEMBL2820341 | 0.83 | MMP13 (0.31) | MMP13TSHR | |
| SCHEMBL2819833 | 0.83 | NMT2 (0.32) | MMP13TSHR | |
| SCHEMBL2822989 | 0.83 | MMP13 (0.31) | MMP13TSHR | |
| SCHEMBL2821657 | 0.82 | KDM4E (0.38) | MMP13TSHR | |
| SCHEMBL2823027 | 0.82 | MMP13 (0.32) | MMP13TSHR | |
| SCHEMBL2826428 | 0.81 | MMP13 (0.33) | MMP13TSHRTNKSPARP1TNKS2 | |
| SCHEMBL2820048 | 0.81 | MMP13 (0.37) | MMP13TSHRTNKSPARP1TNKS2 | |
| SCHEMBL2821666 | 0.80 | RAB9A (0.36) | RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1386914-B1 | HALOGENATED QUINOLINE DERIVATIVES AND ECTOPARASITE CONTROLLERS | MEIJI SEIKA KAISHA (JP) | 2010-10-27 | — | — | EP | disclosed |
| US-7022855-B2 | Halogen-substituted quinoline derivatives and ectoparasite control agent | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-04-04 | — | — | US | disclosed |