SCHEMBL28220073

SCHEMBL28220073

C1=C(CCc2ccccc2)c2ccccc2C1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.53
PARK7 Q99497 1/20 0.43
SIGMAR1 Q99720 2/20 0.41
ALDH1A1 P00352 2/20 0.38
CASP1 P29466 2/20 0.38
HSD17B10 Q99714 2/20 0.38
APAF1 O14727 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
RAB9A P51151 1/20 0.38
BLM P54132 1/20 0.38
CASP7 P55210 1/20 0.38
KMT2A Q03164 1/20 0.38
MAOA P21397 2/20 0.38
MAOB P27338 2/20 0.38
GRIN2B Q13224 1/20 0.37
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.37
ALOX12 P18054 1/20 0.37
HTR2A P28223 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31121639 0.90 HTR6 (0.56) HTR6SIGMAR1MAOAMAOB
SCHEMBL2338975 0.90 HTR6 (0.56) HTR6SIGMAR1MAOAMAOB
SCHEMBL11223271 0.86 HTR6 (0.47) HTR6ALOX15TDP1LOXL2
SCHEMBL6130448 0.82 HTR6 (0.74) HTR6SIGMAR1ALDH1A1CASP1HSD17B10
SCHEMBL3868123 0.82 HTR6 (0.53) HTR6SIGMAR1ALDH1A1MAPTRAB9A
SCHEMBL3874874 0.82 HTR6 (0.53) HTR6SIGMAR1ALDH1A1MAPTRAB9A
SCHEMBL27294942 0.81 SIGMAR1 (0.59) PARK7SIGMAR1ALDH1A1CASP1HSD17B10
SCHEMBL23023190 0.81 GAA (0.53) HTR6SIGMAR1ALDH1A1GAAMAPT
SCHEMBL6683586 0.81 GAA (0.53) HTR6SIGMAR1ALDH1A1GAAMAPT
SCHEMBL1822774 0.78 HTR6 (0.50) HTR6SIGMAR1MAOATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108126753-A Application of a kind of metallocene compound in Allyl end groups oligomerization of propene object is prepared 华东理工大学 2018-06-08 CN disclosed