Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 4/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19661316 | 0.93 | LMNA (0.56) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL31432032 | 0.86 | LMNA (0.59) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL22485568 | 0.86 | BRD4 (0.55) | KDM4EALOX15TSHRTDP1LMNA | |
| SCHEMBL18247275 | 0.86 | P2RX7 (0.64) | KDM4EALOX15TSHRTDP1LMNA | |
| SCHEMBL24638032 | 0.84 | LMNA (0.49) | KDM4EALOX15TSHRTDP1LMNA | |
| SCHEMBL20729906 | 0.84 | LMNA (0.57) | KDM4ELMNACA1CA2POLB | |
| SCHEMBL31431706 | 0.83 | LMNA (0.65) | KDM4EALOX15TSHRACMSDTDP1 | |
| Dipicolinic Acid SCHEMBL27876291 | 0.83 | KDM4E (0.68) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL18246760 | 0.83 | CYP1A2 (0.57) | KDM4ETSHRLMNACNR1ALDH1A1 | |
| SCHEMBL12163955 | 0.82 | P2RX7 (0.69) | KDM4ELMNAPOLBCNR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049326-A1 | TRICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 | BIOCRYST PHARMACEUTICALS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |
| CN-108137545-A | TRIAZOLE AGONISTS OF THE APJ RECEPTOR | 美国安进公司 | 2018-06-08 | — | — | CN | disclosed |