Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18790615 | 0.78 | ALDH1A1 (0.53) | KDM4ETSHRMAPK1RECQLALDH1A1 | |
| SCHEMBL4996049 | 0.78 | MEN1 (0.55) | KDM4ETSHRMAPK1RECQLALDH1A1 | |
| SCHEMBL18064909 | 0.77 | KDM4E (0.44) | KDM4ETSHRALDH1A1SMN1; SMN2HTT | |
| SCHEMBL18064807 | 0.76 | MGLL (0.50) | — | |
| SCHEMBL15214404 | 0.75 | KDM4E (0.55) | KDM4ETSHRMAPK1RECQLALDH1A1 | |
| SCHEMBL18064829 | 0.74 | ALDH1A1 (0.52) | KDM4ETSHRMAPK1RECQLALDH1A1 | |
| SCHEMBL14367287 | 0.74 | SIRT6 (0.49) | KDM4ERECQLALDH1A1SMN1; SMN2POLB | |
| SCHEMBL5651766 | 0.74 | SIRT6 (0.49) | KDM4ERECQLALDH1A1SMN1; SMN2POLB | |
| SCHEMBL18064915 | 0.73 | KDM4E (0.40) | KDM4ETSHRALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL12649065 | 0.73 | KDM4E (0.42) | KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104650049-B | Substituted pyridine compounds and its application method and purposes | 广东东阳光药业有限公司 | 2018-06-08 | — | — | CN | disclosed |