SCHEMBL28220156

SCHEMBL28220156

O=[N+]([O-])c1ccc(O[As](=O)(O)Oc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
LMNA P02545 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
CRHBP P24387 1/20 0.49
ATM Q13315 1/20 0.49
CRHR2 Q13324 1/20 0.49
TLR9 Q9NR96 1/20 0.49
KDM4E B2RXH2 1/20 0.48
DRD2 P14416 1/20 0.48
DRD4 P21917 1/20 0.48
DRD3 P35462 1/20 0.48
CES2 O00748 2/20 0.47
CES1 P23141 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HTT P42858 1/20 0.46
CYP2C19 P33261 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3327337 0.82 CA1 (0.52) ALDH1A1MEN1KMT2ACES2CES1
SCHEMBL2064518 0.81 CA4 (0.46) ALDH1A1L3MBTL1ATMCYP2C19CA1
Ammonia Solution, Strong SCHEMBL28690710 0.80 CA1 (0.50) ALDH1A1LMNAMEN1KMT2ACES2
SCHEMBL26101859 0.79 GSR (0.39) ALDH1A1LMNAMEN1KMT2ACES2
SCHEMBL457863 0.77 HSPB1 (0.68) ALDH1A1LMNAL3MBTL1MEN1KMT2A
Nitrobenzene SCHEMBL28196798 0.77 ALDH1A1 (0.76) ALDH1A1LMNAL3MBTL1MEN1KMT2A
Dinitrophenylene SCHEMBL27976876 0.77 TSHR (0.55) ALDH1A1LMNAMEN1KMT2ACES2
SCHEMBL6322393 0.75 SMN1; SMN2 (0.64) ALDH1A1LMNAKMT2AKDM4ECES2
SCHEMBL20377184 0.75 SMN1; SMN2 (0.64) ALDH1A1LMNAKMT2AKDM4ECES2
SCHEMBL8741192 0.75 ALDH1A1 (0.60) ALDH1A1LMNAMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108002542-A The application of bacterial strain 中国科学技术大学 2018-05-08 CN disclosed