Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.30 |
| ▸ | CES2 | O00748 | 2/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28897087 | 0.83 | TP53 (0.40) | FAAHCES2CES1 | |
| SCHEMBL28219944 | 0.76 | EPHX1 (0.37) | FAAHCES2CES1 | |
| SCHEMBL27848921 | 0.74 | CA1 (0.32) | — | |
| SCHEMBL5310923 | 0.71 | FAAH (0.39) | FAAHCES2CES1 | |
| SCHEMBL6477912 | 0.71 | CA2 (0.32) | — | |
| SCHEMBL27547992 | 0.71 | CA12 (0.34) | — | |
| SCHEMBL17258932 | 0.68 | FAAH (0.50) | FAAHCES2CES1 | |
| SCHEMBL6051182 | 0.67 | CA1 (0.42) | — | |
| SCHEMBL2323817 | 0.65 | FAAH (0.37) | FAAHCES2CES1 | |
| SCHEMBL14084778 | 0.64 | GRIA1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137545-A | TRIAZOLE AGONISTS OF THE APJ RECEPTOR | 美国安进公司 | 2018-06-08 | — | — | CN | disclosed |