Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 11/20 | 0.34 |
| ▸ | CES1 | P23141 | 6/20 | 0.34 |
| ▸ | CES2 | O00748 | 5/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5310923 | 0.86 | FAAH (0.39) | EPHX1ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL17258932 | 0.82 | FAAH (0.50) | EPHX1MEN1KMT2AFAAHCES1 | |
| SCHEMBL27848921 | 0.81 | CA1 (0.32) | EPHX1ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL6477912 | 0.78 | CA2 (0.32) | CA2 | |
| SCHEMBL28220160 | 0.76 | FAAH (0.30) | FAAHCES1CES2 | |
| SCHEMBL6051182 | 0.74 | CA1 (0.42) | SMN1; SMN2CA2 | |
| SCHEMBL2467344 | 0.73 | CA1 (0.51) | ALDH1A1KMT2AFAAHCES1CA2 | |
| SCHEMBL22467467 | 0.73 | ALDH1A1 (0.36) | ALDH1A1HSD17B10 | |
| SCHEMBL28438676 | 0.73 | MGAM (0.40) | CA12CA14 | |
| SCHEMBL31547530 | 0.71 | MGAM (0.33) | ALDH1A1CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137545-A | TRIAZOLE AGONISTS OF THE APJ RECEPTOR | 美国安进公司 | 2018-06-08 | — | — | CN | disclosed |