SCHEMBL28220167

SCHEMBL28220167

C=CC(=O)NCCN=[N+]=[N-]

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
ALDH1A1 P00352 1/20 0.46
MAPK1 P28482 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ZDHHC20 Q5W0Z9 1/20 0.44
ZDHHC2 Q9UIJ5 1/20 0.44
TGM2 P21980 2/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16619465 0.89 ZDHHC20 (0.50) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL20886391 0.83 TSHR (0.38) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL23559867 0.83 ALDH1A1 (0.38) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL15604077 0.78 ZDHHC20 (0.51) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL167051 0.75 TSHR (0.68) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL10952688 0.75 TSHR (0.68) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL19329200 0.74
Acrylamide SCHEMBL28446788 0.73 ZDHHC20 (0.46) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL20746791 0.73 ZDHHC20 (0.50) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL31173909 0.73 ZDHHC20 (0.54) TSHRALDH1A1MAPK1TDP1ZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108126189-A It is classified nano combined carrier delivery system and its application of assembling 中国药科大学 2018-06-08 CN claimed
CN-108126189-B Nano composite carrier drug delivery system assembled in grading manner and application thereof 中国药科大学 2021-03-02 CN disclosed
CN-108126189-A It is classified nano combined carrier delivery system and its application of assembling 中国药科大学 2018-06-08 CN disclosed