SCHEMBL16619465

SCHEMBL16619465

C=CC(=O)NCCCN=[N+]=[N-]

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.50
ZDHHC2 Q9UIJ5 1/20 0.50
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.43
MAPK1 P28482 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MAPT P10636 1/20 0.38
TGM2 P21980 5/20 0.37
GAA P10253 1/20 0.37
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28220167 0.89 TSHR (0.46) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL15604077 0.82 ZDHHC20 (0.51) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL23559867 0.80 ALDH1A1 (0.38) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL20886391 0.80 TSHR (0.38) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL20386602 0.79 APEX1 (0.40) ZDHHC20ZDHHC2ALDH1A1MAPTKMT2A
SCHEMBL28142686 0.79 CA12 (0.31)
SCHEMBL2364074 0.79 ZDHHC20 (0.55) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL31173909 0.77 ZDHHC20 (0.54) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL1561467 0.77 ZDHHC20 (0.68) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL632264 0.77 ZDHHC20 (0.75) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3558384-A1 BIOCOMPATIBLE AND HYDROPHILIC POLYMER CONJUGATE FOR TARGETED DELIVERY OF AN AGENT Commonwealth Scientific and Industrial Research Organisation (AU) 2019-10-30 EP claimed
CN-110366430-A Biocompatible and hydrophilic polymer conjugates for targeted delivery of agents 联邦科学和工业研究组织 2019-10-22 CN claimed
WO-2018112551-A1 BIOCOMPATIBLE AND HYDROPHILIC POLYMER CONJUGATE FOR TARGETED DELIVERY OF AN AGENT COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2018-06-28 WO claimed
US-20250034638-A1 Articles with Photoiniferter Attached to Inorganic Oxide Surface and Polymers Prepared Therefrom 3M INNOVATIVE PROPERTIES COMPANY 2025-01-30 US disclosed
US-10954506-B2 Polymer engineered regenerating bioscavengers CARNEGIE MELLON UNIVERSITY (US) 2021-03-23 US disclosed
US-10947525-B2 Polymer engineered regenerating bioscavengers CARNEGIE MELLON UNIVERSITY (US) 2021-03-16 US disclosed
US-20200309782-A1 INTRACELLULAR DELIVERY VEHICLE KIRIN HOLDINGS KABUSHIKI KAISHA (JP) 2020-10-01 US disclosed
US-10712346-B2 Intracellular delivery vehicle KIRIN HOLDINGS KABUSHIKI KAISHA (JP) 2020-07-14 US disclosed
US-20200131285-A1 NOVEL POLYMERS AND DNA COPOLYMER COATINGS ILLUMINA CAMBRIDGE LIMITED (GB) 2020-04-30 US disclosed
US-10577439-B2 Polymers and DNA copolymer coatings ILLUMINA CAMBRIDGE LIMITED (GB) 2020-03-03 US disclosed
EP-3558384-A1 BIOCOMPATIBLE AND HYDROPHILIC POLYMER CONJUGATE FOR TARGETED DELIVERY OF AN AGENT Commonwealth Scientific and Industrial Research Organisation (AU) 2019-10-30 EP disclosed
US-20190137503-A1 INTRACELLULAR DELIVERY VEHICLE KIRIN KABUSHIKI KAISHA (JP) 2019-05-09 US disclosed
US-10208142-B2 Polymers and DNA copolymer coatings Illumnia Cambridge Limited (GB) 2019-02-19 US disclosed
WO-2018112551-A1 BIOCOMPATIBLE AND HYDROPHILIC POLYMER CONJUGATE FOR TARGETED DELIVERY OF AN AGENT COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2018-06-28 WO disclosed
US-9815916-B2 Polymers and DNA copolymer coatings ILLUMINA CAMBRIDGE LIMITED (GB) 2017-11-14 US disclosed
US-9815916-B2 Polymers and DNA copolymer coatings ILLUMINA CAMBRIDGE LIMITED (GB) 2017-11-14 US disclosed
US-20160244741-A1 POLYMER ENGINEERED REGENERATING BIOSCAVENGERS CARNEGIE MELLON UNIVERSITY 2016-08-25 US disclosed
US-20160122816-A1 NOVEL POLYMERS AND DNA COPOLYMER COATINGS ILLUMINA CAMBRIDGE LIMITED (GB) 2016-05-05 US disclosed
US-20160122816-A1 NOVEL POLYMERS AND DNA COPOLYMER COATINGS ILLUMINA CAMBRIDGE LIMITED (GB) 2016-05-05 US disclosed
WO-2015051326-A1 POLYMER ENGUNEERED REGENERATING BIOSCAVENGERS CARNEGIE MELLON UNIVERSITY (US) 2015-04-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10947525-B2 Polymer engineered regenerating bioscavengers BCHE, ACHE, CES2 ZDHHC20 1712/4885ZDHHC2 1602/4885ALDH1A1 87/4885
US-20160244741-A1 POLYMER ENGINEERED REGENERATING BIOSCAVENGERS BCHE, ACHE, CES2 ZDHHC20 1712/4885ZDHHC2 1602/4885ALDH1A1 87/4885
US-10712346-B2 Intracellular delivery vehicle CHERP, ACTB, GOLT1B ZDHHC20 2159/4885ZDHHC2 2441/4885ALDH1A1 4647/4885
US-20200309782-A1 INTRACELLULAR DELIVERY VEHICLE CHERP, ACTB, GOLT1B ZDHHC20 2159/4885ZDHHC2 2441/4885ALDH1A1 4647/4885
US-20190137503-A1 INTRACELLULAR DELIVERY VEHICLE CHERP, ACTB, GOLT1B ZDHHC20 2159/4885ZDHHC2 2441/4885ALDH1A1 4647/4885
US-10954506-B2 Polymer engineered regenerating bioscavengers BCHE, ACHE, CES2 ZDHHC20 1712/4885ZDHHC2 1602/4885ALDH1A1 87/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.