Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4820728 | 0.86 | PRKCI (0.50) | PRKCICREBBPPKMHTTKMT2A | |
| SCHEMBL4160955 | 0.85 | CREBBP (0.61) | PRKCICREBBPPKMHTTKMT2A | |
| SCHEMBL25590302 | 0.81 | PKM (0.59) | PRKCICREBBPPKMHTTKMT2A | |
| SCHEMBL2876534 | 0.81 | PKM (0.59) | PRKCICREBBPPKMHTTKMT2A | |
| SCHEMBL10687240 | 0.79 | CREBBP (0.55) | PRKCICREBBPPKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL13986277 | 0.79 | PRKCI (0.50) | PRKCICREBBPPKMHTTKMT2A | |
| SCHEMBL1354273 | 0.78 | ALDH1A1 (0.45) | HTTSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL27718572 | 0.77 | PKM (0.46) | PKMHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL13654745 | 0.77 | PRKCI (0.57) | PRKCICREBBPPKMHTTKMT2A | |
| SCHEMBL5159793 | 0.77 | MAPT (0.39) | PKMHTTKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108069911-A | 6- amino -2- phenyl pyrimidine classes compound, preparation method and medical usage | 中国药科大学 | 2018-05-25 | — | — | CN | disclosed |