SCHEMBL4820728

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28220193	0.86	PRKCI (0.50)	PRKCICREBBPPKMKMT2APOLB
	SCHEMBL28763271	0.85	KDM4E (0.49)	HSD17B10KMT2APOLBMEN1ALDH1A1
	SCHEMBL4160955	0.85	CREBBP (0.61)	PRKCICREBBPPKMHSD17B10KMT2A
	SCHEMBL25590302	0.81	PKM (0.59)	PRKCICREBBPPKMHSD17B10KMT2A
	SCHEMBL27862364	0.81	KDM4E (0.58)	PKMHSD17B10POLBALDH1A1MAPT
	SCHEMBL14368281	0.80	NR1H4 (0.55)	PKMHSD17B10KMT2APOLBMEN1
	SCHEMBL10687240	0.79	CREBBP (0.55)	PRKCICREBBPPKMHSD17B10ALDH1A1
	SCHEMBL13986277	0.79	PRKCI (0.50)	PRKCICREBBPPKMHSD17B10KMT2A
	SCHEMBL22491940	0.79	MAOB (0.48)	PKMHSD17B10KMT2APOLBMEN1
	SCHEMBL4814551	0.79	PKM (0.43)	PKMHSD17B10KMT2APOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.