Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL321288 | 0.75 | MAPT (0.75) | POLBMAPTL3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL9937249 | 0.72 | MAPT (0.53) | MAPTMAPK1MEN1KMT2AHTT | |
| SCHEMBL11267717 | 0.71 | MAPT (0.78) | POLBMAPTL3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL11185205 | 0.70 | MAPT (0.56) | POLBMAPTL3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL30733931 | 0.69 | MEN1 (0.41) | POLBMAPTMAPK1MEN1KMT2A | |
| SCHEMBL6218407 | 0.69 | MAPT (0.60) | POLBMAPTL3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL11604911 | 0.69 | MAPT (0.58) | POLBMAPTL3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL29140107 | 0.68 | MEN1 (0.44) | POLBMAPTL3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL3897320 | 0.68 | SMN1; SMN2 (0.55) | POLBMAPTL3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL10948187 | 0.67 | KEAP1 (0.63) | POLBMAPTMAPK1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104906103-B | Casein kinase 1 δ (CK1 δ) inhibitor | 电泳有限公司 | 2018-05-18 | — | — | CN | disclosed |