Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29059891 | 0.76 | ALDH1A1 (0.43) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL1380292 | 0.70 | SRD5A2 (0.44) | MEN1KMT2AMAPTHTTMAPK1 | |
| SCHEMBL28222883 | 0.68 | POLB (0.54) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL3296771 | 0.65 | BCL2L1 (0.65) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL7937415 | 0.65 | LMNA (0.67) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL10513615 | 0.65 | LMNA (0.67) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL1864175 | 0.64 | BCL2L1 (0.70) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL9777084 | 0.64 | BCL2L1 (0.70) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL9814506 | 0.64 | BCL2L1 (0.70) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL9937249 | 0.64 | MAPT (0.53) | MEN1KMT2AMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114671868-B | Polysubstituted indolizine compound containing pyridone and preparation method and application thereof | 浙大城市学院 | 2023-03-31 | — | — | CN | disclosed |