Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 6/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.36 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28536814 | 0.82 | ALDH1A1 (0.50) | SMN1; SMN2KMT2A | |
| SCHEMBL28221203 | 0.82 | LOXL2 (0.53) | LOXL2NOS3NOS1NOS2SMN1; SMN2 | |
| SCHEMBL28031818 | 0.80 | HDAC3 (0.47) | LOXL2HDAC3HDAC6NCOR2F10 | |
| SCHEMBL27913568 | 0.79 | LOXL2 (0.50) | LOXL2HDAC3HDAC6NCOR2F10 | |
| SCHEMBL29290141 | 0.78 | PTGS1 (0.43) | SMN1; SMN2KMT2A | |
| SCHEMBL11427681 | 0.78 | CA1 (0.36) | KDM4ESMN1; SMN2KMT2ACA1CA2 | |
| SCHEMBL5087435 | 0.78 | PTGS1 (0.43) | SMN1; SMN2KMT2A | |
| SCHEMBL28789528 | 0.77 | LOXL2 (0.43) | LOXL2HDAC3HDAC6NCOR2F10 | |
| SCHEMBL27887440 | 0.77 | THRA (0.54) | KMT2A | |
| SCHEMBL9609532 | 0.75 | ALDH1A1 (0.46) | HDAC6SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108117534-A | The oxygen-containing cycloaliphatic ring methylamines of benzo | 华东理工大学 | 2018-06-05 | — | — | CN | disclosed |