Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12435983 | 0.93 | CYP11B1 (0.42) | HSD17B1HSD17B2ENPP3ENPP1MEN1 | |
| SCHEMBL12435750 | 0.89 | CYP11B1 (0.45) | CCNT1CCNA2CDK2CDK9CA12 | |
| SCHEMBL24345100 | 0.86 | KDM4E (0.49) | PIM1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL12435751 | 0.86 | CA12 (0.41) | HSD17B1HSD17B2CA12CA9MEN1 | |
| SCHEMBL17680015 | 0.86 | CYP11B1 (0.41) | CCNT1CCNA2CDK2CDK9CA12 | |
| SCHEMBL13658704 | 0.86 | RAB9A (0.45) | ENPP3ENPP1KDM4EALDH1A1CYP11B1 | |
| SCHEMBL12435976 | 0.85 | CYP11B1 (0.44) | ENPP3ENPP1MEN1KMT2AKDM4E | |
| SCHEMBL12435753 | 0.84 | TNF (0.42) | CA12CA9ENPP3ENPP1MEN1 | |
| SCHEMBL25493550 | 0.84 | KDM4E (0.48) | CCNT1CCNA2CDK2CDK9ENPP3 | |
| SCHEMBL9613088 | 0.84 | CA12 (0.40) | HSD17B1HSD17B2CCNT1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108070004-B | Pyridines anthracene derivant iridium-platinum complex and its synthesis and application | 华中科技大学 | 2019-08-09 | — | — | CN | disclosed |
| CN-108070004-A | Pyridines anthracene derivant iridium-platinum complex and its synthesis and application | 华中科技大学 | 2018-05-25 | — | — | CN | disclosed |