SCHEMBL24345100

SCHEMBL24345100

c1cncc(-c2ccc(-c3c4ccccc4c(-c4cccc5ccccc45)c4ccccc34)cn2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.49
ALDH1A1 P00352 2/20 0.49
MAPT P10636 2/20 0.49
HPGD P15428 2/20 0.49
RAB9A P51151 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
CYP2A6 P11509 4/20 0.46
CYP3A4 P08684 1/20 0.46
CYP11B1 P15538 5/20 0.44
TNF P01375 1/20 0.42
CYP2C9 P11712 2/20 0.41
DHODH Q02127 1/20 0.41
GPR84 Q9NQS5 1/20 0.41
CYP11B2 P19099 4/20 0.40
CYP19A1 P11511 2/20 0.40
CYP17A1 P05093 1/20 0.40
BCHE P06276 1/20 0.40
PIM1 P11309 2/20 0.39
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24345162 0.95 MAPT (0.47) KDM4EALDH1A1MAPTHPGDRAB9A
SCHEMBL15977579 0.90 CYP11B1 (0.46) KDM4EALDH1A1MAPTHPGDRAB9A
SCHEMBL14461162 0.89 ALDH1A1 (0.58) KDM4EALDH1A1MAPTHPGDRAB9A
SCHEMBL15977924 0.89 KDM4E (0.46) KDM4EALDH1A1MAPTHPGDRAB9A
SCHEMBL12435983 0.88 CYP11B1 (0.42) KDM4EALDH1A1MAPTHPGDRAB9A
SCHEMBL2023297 0.87 CYP2A6 (0.58) ALDH1A1CYP2A6CYP3A4CYP11B1CYP2C9
SCHEMBL13658704 0.86 RAB9A (0.45) KDM4EALDH1A1MAPTHPGDRAB9A
SCHEMBL28223142 0.86 HSD17B1 (0.43) KDM4EALDH1A1MAPTHPGDRAB9A
SCHEMBL15977583 0.86 PIK3CA (0.44) KDM4EALDH1A1MAPTHPGDRAB9A
SCHEMBL15977922 0.85 CYP11B1 (0.51) KDM4EALDH1A1MAPTHPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230145851-A1 INTERFACE LAYER DESIGN FOR EFFICIENT AND STABLE WHITE OLEDS UNITED STATES DEPARTMENT OF ENERGY 2023-05-11 US disclosed
US-20230145851-A1 INTERFACE LAYER DESIGN FOR EFFICIENT AND STABLE WHITE OLEDS UNITED STATES DEPARTMENT OF ENERGY 2023-05-11 US disclosed
US-20220102641-A1 FUNCTIONAL MATERIALS FOR OLED APPLICATIONS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2022-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220102641-A1 FUNCTIONAL MATERIALS FOR OLED APPLICATIONS OCIAD1, OGFOD1, SLCO1A2 KDM4E 4188/4885ALDH1A1 1177/4885MAPT 2710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.