SCHEMBL2822333

SCHEMBL2822333

CCCCCCCCCC(OC(=O)c1ccc(C(=O)O)cc1)(C(C)CCCC)C(C)CCCC

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.47
TSHR P16473 1/20 0.47
PLA2G4B P0C869 6/20 0.46
RARB P10826 7/20 0.44
MAPT P10636 2/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
RARA P10276 1/20 0.43
MTOR P42345 1/20 0.43
KMT2A Q03164 1/20 0.43
PLA2G4A P47712 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2919381 0.89 TP53 (0.51) TP53TSHRPLA2G4BRARBMAPT
SCHEMBL3032498 0.81 CYP1A2 (0.47) TP53TSHRALDH1A1
SCHEMBL18817713 0.80 TP53 (0.54) TP53TSHRPLA2G4BRARBMAPT
SCHEMBL4938672 0.78 TP53 (0.51) TP53TSHRPLA2G4BRARBMAPT
SCHEMBL27968723 0.78 TP53 (0.51) TP53TSHRPLA2G4BRARBMAPT
SCHEMBL17982633 0.78 TP53 (0.51) TP53TSHRPLA2G4BRARBMAPT
SCHEMBL4401536 0.76 PLA2G4B (0.46) TP53TSHRPLA2G4BKMT2APLA2G4A
SCHEMBL690294 0.76 TP53 (0.49) TP53TSHRPLA2G4BRARBMAPT
SCHEMBL6232656 0.75 LMNA (0.49) TSHRMAPTMEN1ALDH1A1KMT2A
SCHEMBL6230648 0.75 LMNA (0.49) TSHRMAPTMEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2157159-B1 HYDRAULIC FLUID IDEMITSU KOSAN CO (JP) 2015-12-02 EP disclosed
EP-2674473-A2 Hydraulic fluid and hydraulic system IDEMITSU KOSAN CO., LTD. (JP) 2013-12-18 EP disclosed
US-8299004-B2 Hydraulic fluid and hydraulic system IDEMITSU KOSAN CO., LTD. (JP) 2012-10-30 US disclosed
US-20100130394-A1 HYDRAULIC FLUID AND HYDRAULIC SYSTEM IDEMITSU KOSAN CO., LTD (JP) 2010-05-27 US disclosed
EP-2157159-A1 HYDRAULIC FLUID AND HYDRAULIC SYSTEM Idemitsu Kosan Co., Ltd. (JP) 2010-02-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100130394-A1 HYDRAULIC FLUID AND HYDRAULIC SYSTEM AQP1, AQP3, TECR TP53 1542/4885TSHR 4028/4885PLA2G4B 1788/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.