Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzamide SCHEMBL28875161 | 0.86 | MAPT (0.57) | MAPTL3MBTL1POLBCYP3A4PARP1 | |
| Toluene SCHEMBL9479143 | 0.82 | GAA (0.52) | L3MBTL1TSHRHSD17B10MEN1KMT2A | |
| SCHEMBL9159740 | 0.82 | GAA (0.61) | MAPTL3MBTL1CYP2C19MEN1KMT2A | |
| Benzene SCHEMBL28101102 | 0.82 | GAA (0.67) | TSHRHSD17B10MEN1KMT2ASMN1; SMN2 | |
| Benzamide SCHEMBL27654010 | 0.81 | MAPT (0.59) | MAPTL3MBTL1POLBCYP3A4PARP1 | |
| SCHEMBL28792148 | 0.81 | KMT2A (0.57) | MAPTL3MBTL1POLBCYP3A4CYP2C19 | |
| Benzamide SCHEMBL25180444 | 0.80 | CYP3A4 (0.76) | MAPTL3MBTL1POLBCYP3A4PARP1 | |
| SCHEMBL23149729 | 0.79 | PARP10 (0.53) | MAPTCYP3A4PARP1TSHRMEN1 | |
| Benzamide SCHEMBL27276187 | 0.79 | MAPT (0.57) | MAPTL3MBTL1POLBCYP3A4PARP1 | |
| SCHEMBL124577 | 0.79 | KMT2A (0.59) | MAPTL3MBTL1POLBCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106631867-B | A kind of method for synthesizing 2- benzamido -3- aryl-acrylic acid esters | 河南省科学院化学研究所有限公司 | 2018-06-22 | — | — | CN | disclosed |