Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | PARP1 | P09874 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzophenone SCHEMBL8217631 | 0.85 | ELANE (0.58) | MAPTHSD17B10TSHRTDP1L3MBTL1 | |
| Acetophenone SCHEMBL27892435 | 0.85 | ALDH1A1 (0.56) | MAPTHSD17B10TSHRL3MBTL1MEN1 | |
| Benzoic Acid SCHEMBL8413078 | 0.85 | ALDH1A1 (0.56) | MAPTHSD17B10TSHRMEN1KMT2A | |
| Benzoic Acid SCHEMBL27330443 | 0.85 | ALDH1A1 (0.56) | MAPTHSD17B10TSHRMEN1KMT2A | |
| Benzamide SCHEMBL27276187 | 0.84 | MAPT (0.57) | MAPTHSD17B10TSHRPARP1POLB | |
| Ethyl Acetate SCHEMBL5925615 | 0.84 | LMNA (0.62) | MAPTHSD17B10TSHRPARP1CYP3A4 | |
| Benzamide SCHEMBL28875161 | 0.84 | MAPT (0.57) | MAPTHSD17B10TSHRPARP1POLB | |
| Ethyl Benzoate SCHEMBL27407882 | 0.83 | LMNA (0.61) | MAPTHSD17B10TSHRCYP3A4TDP1 | |
| Benzamide SCHEMBL28263471 | 0.82 | PARP1 (0.67) | MAPTHSD17B10TSHRPARP1POLB | |
| Benzamide SCHEMBL4408659 | 0.82 | PARP1 (0.67) | MAPTHSD17B10TSHRPARP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100427472-C | Aryl-heteroaromatic compounds, compositions containing them and their use | AVENTIS PHARMA SA (FR) | 2008-10-22 | — | — | CN | disclosed |
| CN-1829697-A | Aryl-heteroaromatic products, compositions containing same and use thereof | AVENTIS PHARMA SA (FR) | 2006-09-06 | — | — | CN | disclosed |